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autophagy activator rapa  (MedChemExpress)


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    MedChemExpress autophagy activator rapa
    Autophagy Activator Rapa, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1630 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/autophagy activator rapa/product/MedChemExpress
    Average 99 stars, based on 1630 article reviews
    autophagy activator rapa - by Bioz Stars, 2026-02
    99/100 stars

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    Rapamycin alleviates lead‐induced neurological dysfunction by promoting autophagy. SH‐SY5Y cells were pre‐treated with 1 μM Rapamycin (RAPA) for 4 h followed by exposure to 50 μM Pb for 24 h. (A) Detection of Nrf2, Keap1, and HO‐1 proteins by Western blot. (B) Detection of P62, LC3, P‐Tau and total Tau proteins by Western blot. Quantitative data was presented as mean ± SD ( n = 3) and analyzed by one‐way ANOVA.

    Journal: CNS Neuroscience & Therapeutics

    Article Title: The Role of P62 /Nrf2/Keap1 Signaling Pathway in Lead‐Induced Neurological Dysfunction

    doi: 10.1111/cns.70566

    Figure Lengend Snippet: Rapamycin alleviates lead‐induced neurological dysfunction by promoting autophagy. SH‐SY5Y cells were pre‐treated with 1 μM Rapamycin (RAPA) for 4 h followed by exposure to 50 μM Pb for 24 h. (A) Detection of Nrf2, Keap1, and HO‐1 proteins by Western blot. (B) Detection of P62, LC3, P‐Tau and total Tau proteins by Western blot. Quantitative data was presented as mean ± SD ( n = 3) and analyzed by one‐way ANOVA.

    Article Snippet: To enhance cellular autophagy, SH‐SY5Y cells exposed to Pb were pretreated with the autophagy activator Rapamycin (RAPA) (MCE, HY‐10219) [ ].

    Techniques: Western Blot